Nectin-4 has been successfully established as a target molecule in locally advanced and metastatic bladder cancer. An antibody-drug conjugate (enfortumab-vedotin) directed against nectin-4 has shown marked tumor remission ...
Nov 3, 2022
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6
In a new study, scientists have uncovered the mechanics of the blood-tumor barrier, one of the most significant obstacles to improving treatment efficacy and preventing the return of cancerous cells. The research team, led ...
Nov 1, 2022
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603
You may not realize it, but each time you recall a memory—like your first time riding a bike or walking into your high school prom—your brain changes the memory ever so slightly. It's almost like adding an Instagram filter, ...
Oct 3, 2022
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221
Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively ...
Sep 28, 2022
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81
In a new University at Buffalo-led study, scientists propose a new role for the huntingtin protein (HTT), which causes Huntington's disease when mutated.
Sep 27, 2022
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7
Duchenne muscular dystrophy (DMD) is caused by a genetic mutation and affects one in every 5,000 boys born. Because the affected gene is on the X chromosome, girls are carriers of the mutant gene but develop the disease only ...
Sep 27, 2022
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982
Glioblastoma, the most common cancerous brain tumor in adults, is an aggressive disease—patients survive an average of just 15 months once they are diagnosed. Despite more than two decades of research on the causes and ...
Sep 26, 2022
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59
Placental malaria as a consequence of Plasmodium falciparum infections can lead to severe complications for both mother and child. Each year, placental malaria causes nearly 200,000 newborn deaths, mainly due to low birth ...
Sep 26, 2022
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27
Researchers at the University of Gothenburg have been studying the mucus involved in defending the intestines and airways against infection for more than 30 years. To date, their work has focused very much on the large intestine, ...
Sep 23, 2022
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61
A study led by researchers at the University of Arizona Health Sciences discovered new information about the inner workings of the immune system that could have a profound impact on T cell therapies for cancer and other diseases.
Sep 7, 2022
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