The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don't eat me" signal, which tells the immune ...
Oct 12, 2021
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Researchers in Japan have developed a vaccination strategy in mice that promotes the production of antibodies that can neutralize not only SARS-CoV-2 but a broad range of other coronaviruses as well. If successfully translated ...
Oct 8, 2021
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A family of proteins best known for their role in diminishing HIV infectivity may have the goods to outwit other emerging and re-emerging viruses, scientists have found.
Sep 14, 2021
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T cells rely on surface proteins called T cell receptors (TCRs) to bind to and destroy viruses, cancer cells, and other invaders in the body. T cells that infiltrate tumors, however, can have varied, sometimes ineffective ...
Jul 27, 2021
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T-cell acute lymphoblastic leukemia (T-ALL) is a very aggressive type of blood cancer. It is relatively rare but still draws a lot of attention as it mostly develops in children under the age of 20. The standard treatment ...
May 4, 2021
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In cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of the most significant recent advances in immunotherapies targeted at cancer.
Mar 18, 2021
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Proteins control almost all vital processes in our cells. If they do not function correctly, if there is too much or too little of them, this can lead to the development of a variety of diseases including cancer. The associated ...
Mar 9, 2021
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Small cell lung cancer (SCLC) cells are missing a surface protein that triggers an immune response, allowing them to hide from one of the body's key cancer defenses, a new study led by UT Southwestern researchers suggests. ...
Jan 25, 2021
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Researchers at McGill University have identified a new cellular pathway that limits the growth and spread of brain tumors by controlling the recycling of cell surface receptor proteins. The study, which will be published ...
Jan 14, 2021
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Signals from two key proteins are essential for the survival of our 'immunological memory', according to new research from scientists at the Francis Crick Institute, published in the Journal of Experimental Medicine.
Oct 30, 2020
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