Alzheimer's disease & dementia

Uncovering the unusual way aggregates hijack proteins

Utrecht scientists have uncovered how aggregates alter the behavior of Tau protein, known to play a role in Alzheimer's disease. On a molecular level, the researchers have revealed why certain proteins tend to bind to Tau ...

Diseases, Conditions, Syndromes

A new treatment strategy against MERS

First identified in 2012, the MERS-coronavirus is capable of causing severe and often fatal pneumonia. There are no effective treatments for MERS. Researchers from the German Center for Infection Research (DZIF) at Charité ...

Neuroscience

Molecular bodyguards against Parkinson's disease

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson's disease. A disturbed relationship to these "bodyguards" leads to cell damage and the formation ...

Gerontology & Geriatrics

Why ageing should be classified as a disease

Since the time of the ancient Greeks, doctors and philosophers have argued whether ageing is a disease or a natural process. Many authors of the Hippocratic Corpus argued that growing old invariably leads to frailty, disability ...

Neuroscience

How Alzheimer's disease spreads through the brain

Tau can quickly spread between neurons but is not immediately harmful, according to research in mouse neurons published in JNeurosci. Intervening during the initial accumulation of tau could potentially halt the progression ...

Oncology & Cancer

Clues from DNA could predict growth of prostate cancer

Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men's genomes—the complete set of genetic material ...

Neuroscience

Interactive zebrafish brain

If zebrafish larvae used the internet, they might soon be able to download a map of their entire brain. "We're not at that point yet," explains Michael Kunst from the Max Planck Institute of Neurobiology. "Nevertheless, our ...

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