A review published in the journal Molecular Biomedicine provides a comprehensive overview of the METTL family, a group of methyltransferase-like proteins crucial for cellular function. METTL family members are widely distributed ...
Aug 20, 2024
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Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material in our genes that act as highly accurate ...
Aug 19, 2024
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Epigenetics, a term coined by Conrad H. Waddington in the early 1940s, originally described the complex molecular pathways that govern how a genotype manifests as a phenotype. Over time, this definition has evolved to focus ...
May 31, 2024
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A new research paper titled "Exploring the effects of dasatinib, quercetin, and fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions" has been published in Aging.
Mar 6, 2024
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A new population-based study led by CHU Sainte-Justine researcher and Université de Montréal medical professor Tomas Paus reveals the roles of maternal and fetal genes in the growth of a baby's cerebral cortex.
Feb 19, 2024
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Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy. ...
Feb 8, 2024
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Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, aging, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA replication ...
Jan 10, 2024
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Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication.
Oct 11, 2023
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You likely know someone who seems to age slowly, appearing years younger than their birth date suggests. And you likely have seen the opposite—someone whose body and mind seem much more ravaged by time than others. Why ...
Jul 7, 2023
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A new research paper titled "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex" has been published in Aging.
Jun 13, 2023
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