Chemotherapies are cancer treatments that work by inducing lesions in the DNA of tumour cells in order to inhibit their proliferation. However, the body naturally tries to repair these lesions, and thus reduces the efficacy ...
Feb 20, 2014
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A new research paper titled "Gene expression signatures of human senescent corneal and conjunctival epithelial cells" has been published in Aging.
Oct 2, 2023
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A protein known to regulate how cells process glucose also appears to be a tumor suppressor, adding to the potential that therapies directed at cellular metabolism may help suppress tumor growth. In their report in the Dec. ...
Dec 6, 2012
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(Medical Xpress)—Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have identified tissue mechanisms that may influence a woman's susceptibility or resistance to breast ...
Oct 16, 2012
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Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this ...
May 7, 2013
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Researchers in Singapore are gaining further insight into how the mechanical environment of cells drives fundamental cellular processes such as motility, growth and survival. These processes are integral to many clinical ...
Mar 19, 2015
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Cells are capable of translating mechanical changes into biological responses. This process is known as mechanotransduction and plays a fundamental role in the progression of solid tumors, such as breast cancer.
Sep 14, 2023
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In people with Alzheimer's disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain.
Nov 27, 2023
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Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer. According to the newly published study, R-spondin, which enhances the growth of healthy cells in the gut, ...
Sep 23, 2020
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Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer ...
May 7, 2012
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