An international consortium of researchers from Australia, Ireland, the UK, Europe, and Canada, has painstakingly mapped an intracellular network that could open the door to discovering new targeted treatments for colorectal ...
Jan 24, 2020
0
114
Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson's disease. A disturbed relationship to these "bodyguards" leads to cell damage and the formation ...
Dec 4, 2019
0
59
Down syndrome is the most common genetic cause of intellectual disability, and currently there is no effective treatment. Memory deficits are a hallmark of this condition and a study published today in the journal Science ...
Nov 14, 2019
0
144
A new imaging technique that makes it possible to match motor proteins with the cargo they carry within a cell is upending a standard view of how cellular traffic reaches the correct destination. The research, which focuses ...
Oct 22, 2019
0
148
Heart disease remains the most common cause of death in the western world, and cardiac defects are the most prevalent form of birth defect in the United States and Europe. Yet little is known about the proteins and cellular ...
Sep 10, 2019
0
3
Amyotrophic lateral sclerosis (ALS) is a neurological condition that affects motor neurons—the nerve cells that control breathing and muscles. Under a microscope, researchers have noticed that the motor neurons of patients ...
Jul 1, 2019
0
0
Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene—which is often overexpressed in cancer—finding that when it acts with a specific protein, it can lead to cancer cell death. The study ...
May 1, 2019
0
3
Scientists at the RIKEN Center for Brain Science (CBS) have discovered that when a normal cellular cleanup process is disrupted, mice start behaving in ways that resemble human symptoms of autism spectrum disorder (ASD) and ...
Apr 10, 2019
0
256
Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not ...
Apr 9, 2019
0
22
UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.
Mar 22, 2019
0
449
