Oncology & Cancer

New knowledge on molecular mechanisms behind breast cancer

Researchers at University of Copenhagen have gained more insight into the molecular mechanisms of importance for, for example, cancer cell growth and metastasis. The research objective is improved and more targeted drugs. ...

Neuroscience

Autism gene stunts neurons, but growth can be restored, in mice

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches ...

Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Immunology

Rapid recall to fight familiar foes

The immune system's first encounter with a potential threat is a valuable learning experience. Through a process of genetic recombination, our immune B cells can potentially produce a wide array of B cell receptor (BCR) molecules, ...

Medical research

Scientists find 3D structure of key drug target for diabetes

An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney ...

Medical research

Researchers design variant of main painkiller receptor

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

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