Inflammatory disorders

Natural metabolite can suppress inflammation

An international group of scientists from the U.S., Canada, Germany and Russia has revealed a naturally occurring organic compound that can suppress the pro-inflammatory activity of macrophages. The compound, itaconate, is ...

Diseases, Conditions, Syndromes

High iron, copper levels block brain-cell DNA repair

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions. One is ...

Alzheimer's disease & dementia

New clues to Alzheimer's disease

Researchers probing the complexities of Alzheimer's disease have detected issues involving cellular energy production, and those problems may be an important contributor to the late-onset form of the illness.

Immunology

Mitochondrial respiratory chain sustains inflammation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain—a series of protein complexes essential for a cellular respiration and energy production—is necessary for the activation ...

Oncology & Cancer

Specific gene predicts higher chance of surviving prostate cancer

According to Statistics Austria about 5,600 men are diagnosed with prostate cancer in Austria every year, meaning it accounts for roughly a quarter of all cancers in men. For some the cancer develops slowly and requires minimal ...

Neuroscience

Serotonin boosts neuronal powerplants protecting against stress

Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. Collaborative research by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam ...

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