(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Jan 22, 2013
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Knocking out a single enzyme dramatically cripples the ability of aggressive cancer cells to spread and grow tumors, offering a promising new target in the development of cancer treatments, according to a new study by researchers ...
Aug 26, 2013
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A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Mar 8, 2013
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As an extremely aggressive form of skin cancer, cutaneous melanoma, is still associated with a high mortality rate. Enormous progress has recently been made in the fight against deadly metastasis, but existing therapeutic ...
Nov 21, 2023
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Individuals who experienced maltreatment in childhood—such as emotional, physical, and sexual abuse or emotional and physical neglect—are more likely to develop mental illness throughout their entire lives, but it is ...
Apr 11, 2024
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A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria ...
Apr 10, 2013
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Researchers have identified a bacterial protein that triggers a self-inflicted cell death pathway in immune system cells and could lead to a better understanding of an important cellular structure.
Mar 17, 2015
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Neurodegenerative diseases are characterized by the aggregation of misfolded proteins, which accumulate to form insoluble clumps within or around nerve cells. In the adult motor neuron disease amyotrophic lateral sclerosis ...
Apr 22, 2013
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Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States and is thought to affect almost three million people in the UK. New research published in BioMed Central's open access ...
Aug 31, 2012
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The ability to see through organs and even the entire body to visualize long-range connections between cells as well as fine-grained cellular structures has been a long-time dream of biologists. A study published by Cell ...
Jul 31, 2014
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