Oncology & Cancer

Study tests new vaccine for precancerous cervical cells

Vanderbilt University Medical Center is participating in an international study to determine the effectiveness of a new therapeutic vaccine for treating women with precancerous changes on the cervix.

Obstetrics & gynaecology

At-home self-collected samples valid for detecting high-risk HPV

(HealthDay)—Mail-based, at-home self-collection of cervicovaginal samples is valid for detecting high-risk human papillomavirus (HPV) among infrequently screened women, according to a study published online Nov. 5 in Obstetrics ...

Oncology & Cancer

HPV cervical CA screening cuts odds of later CIN3+ diagnosis

(HealthDay)—The use of primary human papillomavirus (HPV) testing versus cytology results in reduced likelihood of cervical intraepithelial neoplasia (CIN) grade 3 or worse (CIN3+) at 48 months, according to a study published ...

Oncology & Cancer

Risk of CIN3 drops with negative HPV, cytology co-tests

(HealthDay)—The five-year risks of cervical intraepithelial neoplasia grade 3 (CIN3), adenocarcinoma in situ, and cervical cancer (≥CIN3) decrease after each successive negative human papillomavirus (HPV) and cytology ...

Obstetrics & gynaecology

First-void morning urine not necessary for CIN2+ detection

(HealthDay)—There is no advantage in testing morning first-void urine over later samples for cervical intraepithelial neoplasia grade 2+ (CIN2+) detection using human papillomavirus (HPV) testing, according to a study published ...

Diseases, Conditions, Syndromes

Poor sensitivity for HPV 16/18 in minor abnormal cytology

(HealthDay)—Testing for human papillomavirus (HPV) 16/18 has poor sensitivity for triaging women with minor abnormal cytology, according to a meta-analysis published online Nov. 15 in the Annals of Internal Medicine.

Oncology & Cancer

Low incidence of cervical cancer, CIN3+ for HPV-negative women

(HealthDay)—Human papillomavirus (HPV)-negative women have low long-term incidence of cervical cancer and cervical intraepithelial neoplasia (CIN) grade 3 or worse (CIN3+), which supports an extension of the cervical screening ...

Oncology & Cancer

Risk of noncervical anogenital cancer up with history of CIN2/3

(HealthDay)—Women with a history of cervical intraepithelial neoplasia (CIN)2 or CIN3 have increased risks of subsequent development of anal, vulvar, and vaginal cancers, according to a study published online June 29 in ...

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