Medical research

Alzheimer's and an unusual molecular chaperone

Among the hallmarks of Alzheimer's disease are the Alzheimer fibrils, deposits of the tau protein, which accumulate in nerve cells in the form of fibres and disrupt communication between nerve cells. But how does this fibre ...

Neuroscience

Molecular bodyguards against Parkinson's disease

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson's disease. A disturbed relationship to these "bodyguards" leads to cell damage and the formation ...

Health

Host-microbe interactions in the gut

Although the mutually beneficial relationship between human beings and gut microbes is clear, how we—the host—affect the functions of gut microbial communities remains poorly understood.

Medical research

How molecular escorts help prevent cancer

The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research conducted at Technical University of Munich (TUM) shows ...

Medical research

Obese mice lose a third of their fat using a natural protein

To the great surprise of cancer researchers, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism. The Georgetown University-led study found that forced expression ...

Parkinson's & Movement disorders

Study identifies chaperone protein implicated in Parkinson's disease

Reduced levels of a chaperone protein might have implications for the development and progression of neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, according to new research from investigators ...

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