Oncology & Cancer

Epigenetic treatments: New allies for chemotherapies?

If genetics is interested in gene sequencing, epigenetics studies how genes are going to be used, or not used, by a cell. The epigenome of a cell represents the set of chemical modifications of the DNA or associated proteins ...

Oncology & Cancer

Peptide mutants may help to identify vulnerability in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins ...

Medical research

Can toxicity of a DNA drug be predicted and minimized?

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence ...

Medical research

'Molecular flashlight' illuminates brain tumors in mice

In a breakthrough that could have wide-ranging applications in molecular medicine, Stanford University researchers have created a bioengineered peptide that enables imaging of medulloblastomas, among the most devastating ...

Medical research

Prenatal intervention reduces learning deficit in mice

Mice with a condition that serves as a laboratory model for Down syndrome perform better on memory and learning tasks as adults if they were treated before birth with neuroprotective peptides, according to researchers at ...

Genetics

New technique could transform epigenetics research

(Medical Xpress) -- Collaboration between scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that will significantly improve scientists' ability to perform epigenetics research ...

Medical research

New powerful tool measures metabolites in living cells

By engineering cells to express a modified RNA called "Spinach," researchers have imaged small-molecule metabolites in living cells and observed how their levels change over time. Metabolites are the products of individual ...

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