From the DNA of nearly 300,000 veterans, scientists have singled out a handful of genetic mutations that not only govern levels of cholesterol, but may also inform the development and use of drugs for cardiovascular disease ...
Oct 1, 2018
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50
UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream—potentially revealing a new pathway ...
Nov 9, 2023
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50
An antioxidant drug reverses atherosclerosis and could be used to prevent heart attacks and strokes due to clots, according to research funded by the British Heart Foundation (BHF) and published today in JAHA: Journal of ...
Sep 9, 2021
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A team of researchers at British Pharmaceutical company AstraZeneca has developed a new antibody drug that increases the level of lipoprotein cholesterol (HDL-C) in test monkeys and humans. In their paper published in the ...
An injectable drug used to reduce stubbornly high cholesterol levels appears in animal studies to also enhance the immune response of anti-cancer therapies known as immune checkpoint inhibitors, a study led by Duke Health ...
Nov 12, 2020
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143
An experimental antibody drug that targets one of the body's key metabolism regulators may help obese people lose weight—at least briefly.
Nov 3, 2020
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38
Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision—or developing new drugs—requires knowing which genes are involved in disease.
May 4, 2020
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142
A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer's disease, and Vanderbilt University biochemist F. Peter Guengerich, Ph.D., is aiding efforts to make this approach to improving ...
Dec 16, 2019
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250
A new drug developed at Yale reduces a host of abnormalities associated with metabolic syndrome, an obesity-born condition that afflicts one of three adults in the United States, researchers report Oct. 2 in the journal Science ...
Oct 3, 2019
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235
There could be new treatments on the horizon for diffuse intrinsic pontine glioma, or DIPG, a devastating form of brain cancer that afflicts young children and is currently incurable. Recent experiments in animal models of ...
Apr 4, 2019
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