Medical research

How exercise reduces belly fat in humans

Some of you may have made a New Year's resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 ...

Health

Cinnamon is highly beneficial according to a new study

Cinnamon might be the oldest known spice in the world. In ancient Egypt, it was once valued more highly than gold. Cinnamon is used in nearly every holiday treat during the fall and winter, but there are plenty of benefits ...

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Cholesterol

Cholesterol is a lipidic, waxy steroid found in the cell membranes and transported in the blood plasma of all animals. It is an essential component of mammalian cell membranes where it is required to establish proper membrane permeability and fluidity. Cholesterol is the principal sterol synthesized by animals, but small quantities are synthesized in other eukaryotes, such as plants and fungi. It is almost completely absent among prokaryotes, which include bacteria. Cholesterol is classified as a sterol.

Since cholesterol is essential for life, it is primarily synthesized de novo within the body. However excessive levels of cholesterol in blood circulation are strongly associated with progression of atherosclerosis. For an adult, typical total body cholesterol synthesis is about 1 gram per day (less if dietary intake is high) and total body cholesterol content is about 35 g. Average dietary intake in western societies is 0.2 - 0.3 grams. Cholesterol is excreted by the liver via the bile into the digestive tract. Typically about 50% of the excreted cholesterol is reabsorbed by the small bowel back into the blood stream.

The name cholesterol originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as François Poulletier de la Salle first identified cholesterol in solid form in gallstones, in 1769. However, it was only in 1815 that chemist Eugène Chevreul named the compound "cholesterine".

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