A new research paper titled "Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes" has been published in Aging.
Sep 20, 2023
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Growth plates (GP), situated at the ends of long bones in children, supply chondrocytes necessary for bone growth. Damage to the growth plate due to fractures often results in arrested bone growth, making it a significant ...
Jul 25, 2023
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Researchers have long known there are sex disparities when it comes to the prevalence and severity of knee osteoarthritis, a disease that causes cartilage degeneration. Now, investigations underway at UT Southwestern Medical ...
May 1, 2023
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Articular cartilage is a connective tissue lining the surfaces of joints. When the cartilage severely wears down, it leads to osteoarthritis (OA), a debilitating disease that affects millions of people globally.
Jun 22, 2021
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An unfortunate biological "feed-forward" loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington University in Saint Louis.
Mar 22, 2021
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A disease of the joints, osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in the United States. In a new study, scientists have discovered the cellular pathway that leads to ...
Feb 10, 2021
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Osteoarthritis (OA), a widely acknowledged cause of disability that affects patients' quality of life and has significant economic impact through healthcare costs and loss of earnings. In a novel study researchers have identified ...
Nov 12, 2020
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Scientists have reported an advanced imaging technique that allows the condition of joint cartilage to be examined—right down to the molecular level. The technique has potential for diagnostics and treatment-planning of ...
Mar 14, 2019
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In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden reports that bone growth in mice takes place in accordance with the same principles as when ...
Feb 27, 2019
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Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...
