Medical research

How a virus destabilizes the genome

New insights into how Kaposi's sarcoma-associated herpesvirus (KSHV) induces genome instability and promotes cell proliferation could lead to the development of novel antiviral therapies for KSHV-associated cancers, according ...

Oncology & Cancer

Tumor cells evade death through in extremis DNA repair

Greater knowledge of the mechanisms that contribute to the survival of tumour cells is key to vanquishing them. The study published today in the journal Cancer Cell, headed by Angel R. Nebreda, ICREA researcher at the Institute ...

Oncology & Cancer

How cancer metastasis happens: Researchers reveal a key mechanism

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial ...

Oncology & Cancer

Study finds potential new biomarker for cancer patient prognosis

To treat or not to treat? That is the question researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) hope to answer with a new advance that could help doctors and their cancer patients ...

Medical research

TERRA, the RNAs that protect telomeres

Despite their especially compact and inaccessible structure, telomeres transcribe information like the rest of the DNA. The RNAs resulting from this process are called TERRA, and their function is essential in preserving ...

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