Vaccination

Increase in hepatitis A vaccination needed to prevent deaths

Nearly two-thirds of those with hepatitis A virus (HAV)-related deaths have at least one documented indication for HAV vaccine, and only 4% have evidence of vaccination, according to research published in the Oct. 20 issue ...

Diseases, Conditions, Syndromes

'Humanized' liver in mice reveals roots of chronic diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting ...

Diseases, Conditions, Syndromes

How to achieve a functional cure for chronic hepatitis B

More than half of people with chronic hepatitis B have a form of the disease in which the immune system almost never achieves sustained control, despite many years of treatment. According to current knowledge, those affected ...

Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

page 5 from 35