Northwestern Medicine scientists have uncovered how peptides produced by bones during inflammation prevent anemia in mice, according to a recent study published in the journal Blood.
May 26, 2023
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A new study published this month in Multiple Sclerosis Journal found a pro-inflammatory diet is associated with an increased risk of relapse in multiple sclerosis (MS) patients. The researchers found a more pro-inflammatory ...
May 24, 2023
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New research is shedding light on global disparities in mortality rates from late-stage liver disease, also called cirrhosis. The study, published May 22 in The Lancet Gastroenterology & Hepatology, revealed that the risk ...
May 24, 2023
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Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis) and the resulting liver cancer are driven by auto-aggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what is behind ...
May 23, 2023
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Inhibiting a protein on the surface of immune cells could offer new strategies for treating severe asthma, Cleveland Clinic researchers found.
May 10, 2023
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Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disorder that progresses slowly and is characterized by cough, asthma, dyspnea and shortness of breath. Previous studies have shown that cigarette smoke ...
May 4, 2023
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A treatment to prevent runaway inflammation in patients with severe COVID-19 is a step closer after a University of Queensland-led study into how immune cells respond to the virus.
May 3, 2023
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Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.
May 2, 2023
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A team of international scientists led by the Heidelberg University, Medical Faculty Mannheim, and the Newcastle University (Great Britain) has succeeded in decoding a new mechanism of immune cell trafficking by examining ...
Apr 25, 2023
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The risk of developing lymphoma is slightly elevated in inflammatory bowel disease (IBD) and has increased in recent years in patients with Crohn's disease, report researchers from Karolinska Institutet in a study published ...
Apr 21, 2023
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Inflammation (Latin, inflamatio, to set on fire) is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. Inflammation is not a synonym for infection. Even in cases where inflammation is caused by infection, the two are not synonymous: infection is caused by an exogenous pathogen, while inflammation is the response of the organism to the pathogen.
In the absence of inflammation, wounds and infections would never heal and progressive destruction of the tissue would compromise the survival of the organism. However, an inflammation that runs unchecked can also lead to a host of diseases, such as hay fever, atherosclerosis, and rheumatoid arthritis. It is for that reason that inflammation is normally closely regulated by the body.
Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes from the blood into the injured tissues. A cascade of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells which are present at the site of inflammation and is characterised by simultaneous destruction and healing of the tissue from the inflammatory process.
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