Oncology & Cancer

Prostaglandin E1 inhibits leukemia stem cells

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

Oncology & Cancer

Protein network signals found to drive myeloid leukemias

Researchers have uncovered how mutations in a protein network drive several high-risk leukemias, offering new prospects for novel therapies. An existing drug might be repurposed to treat these leukemias, and the new understanding ...

Oncology & Cancer

Dasatinib excels in worldwide phase II trial against pediatric CML

In 2002, the FDA approved the drug imatinib as a first-line therapy for adults with chronic myeloid leukemia (CML) caused by the fusion gene BCR-ABL, known as the Philadelphia chromosome. The approval dramatically extended ...

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