Genetic mutations affecting a single gene play an outsized role in Parkinson's disease. The mutations are generally responsible for the mass die-off of a set of dopamine-secreting, or dopaminergic, nerve cells in the brain ...
Nov 15, 2018
0
8
An antenna-like structure on cells, once considered a useless vestige, appears to be important for proper brain development in mammals and when impaired can cause defects in the brain's wiring similar to what's seen in autism, ...
Aug 7, 2017
0
2
Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early ...
Sep 8, 2022
0
79
Danish researchers have just published findings that explain a previously unknown mechanism used by cells to communicate with one another. The research significantly contributes to understanding why some children are born ...
Jun 8, 2013
0
0
Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular functions.
Aug 20, 2020
0
3
Researchers have discovered how a gene commonly linked to obesity—FTO—contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like ...
May 22, 2014
0
0
Sylvia Hoff, a graduate student from the Spemann Graduate School of Biology and Medicine (SGBM), has identified a new gene that causes cystic kidneys in children and young adults. The work by the PhD student Sylvia Hoff and ...
Sep 6, 2013
0
0
Until recently, scientists believed that the primary cilium—an antenna-like structure found on the surface of most human cells—was largely vestigial and had little bearing on the day-to-day lives of human beings. But ...
Feb 25, 2021
0
4
A new study has investigated the expression of the primary cilium in mesothelioma, finding that primary cilia is preferentially lost in the more aggressive subtype of mesothelioma and further research may confirm its potential ...
Oct 27, 2022
0
12
