Medications

Why a common antibiotic treating diarrhea is failing

In the world of superbugs (bacteria that has grown resistant to antibiotics) Clostridioides difficile, a bacterium that causes diarrhea and colitis, is among the most stubborn. In 2013 the Centers for Disease Control called ...

Diseases, Conditions, Syndromes

Researchers discover potential antidote to botulism

Researchers have identified a compound that strongly inhibits botulinum neurotoxin, the most toxic compound known. That inhibiting compound, nitrophenyl psoralen (NPP), could be used as a treatment to reduce paralysis induced ...

Diseases, Conditions, Syndromes

C. difficile tied to increased graft loss in solid organ recipients

(HealthDay)—For solid organ transplant (SOT) recipients, Clostridium difficile infection (CDI) is associated with increased graft loss, according to a study published in the July issue of the American Journal of Transplantation.

Medical research

Compounds kill C. diff, don't affect other gut bacteria in vitro

NC State researchers developed a drug-testing pipeline to help identify compounds that worked against the three stages of Clostridium difficile infection, and found that a compound that holds promise for treating antibiotic-resistant ...

Diseases, Conditions, Syndromes

Dal epidemiologist shows probiotics prevent C. difficile in hospital

Hospitalized patients at high risk for C. difficile infection—a species of bacterium with symptoms that range from diarrhea to life-threatening inflammation of a colon—should be recommended probiotics, says Dr. Bradley ...

Diseases, Conditions, Syndromes

C. difficile risk higher with stoma reversal versus colectomy

(HealthDay)—Patients who undergo elective stoma reversal have a higher incidence of postoperative Clostridium difficile infection versus patients who undergo elective colectomy, according to a study published in the May ...

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Clostridium

Clostridium is a genus of Gram-positive bacteria, belonging to the Firmicutes. They are obligate anaerobes capable of producing endospores. Individual cells are rod-shaped, which gives them their name, from the Greek kloster (κλωστήρ) or spindle. These characteristics traditionally defined the genus, however many species originally classified as Clostridium have been reclassified in other genera.

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