A modified version of the Clostridium novyi (C. noyvi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer ...
Aug 13, 2014
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Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previously ...
Dec 9, 2012
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Researchers at the David Geffen School of Medicine at UCLA and the University of Texas Medical Branch at Galveston have discovered a molecular process by which the body can defend against the effects of Clostridium difficile ...
Aug 21, 2011
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Intermittent fasting changes the gut bacteria activity of mice and increases their ability to recover from nerve damage.
Jun 27, 2022
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While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum—the most potent toxins known. These toxins are often found in contaminated food ...
Jan 8, 2021
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Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells (IECs), thus destroying the protective mucosal ...
Nov 21, 2018
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Researchers have identified a compound that strongly inhibits botulinum neurotoxin, the most toxic compound known. That inhibiting compound, nitrophenyl psoralen (NPP), could be used as a treatment to reduce paralysis induced ...
Nov 2, 2018
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NC State researchers developed a drug-testing pipeline to help identify compounds that worked against the three stages of Clostridium difficile infection, and found that a compound that holds promise for treating antibiotic-resistant ...
Jun 28, 2018
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Researchers from the University of California, Irvine and Harvard University have discovered how the Clostridium difficile toxin B (TcdB) recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells ...
May 11, 2018
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(Medical Xpress)—A small team of researchers at the University of Maryland, some with affiliations to the Veterans Affairs Maryland Health Care System, has written and published a Policy Forum piece in the journal Science ...
Clostridium is a genus of Gram-positive bacteria, belonging to the Firmicutes. They are obligate anaerobes capable of producing endospores. Individual cells are rod-shaped, which gives them their name, from the Greek kloster (κλωστήρ) or spindle. These characteristics traditionally defined the genus, however many species originally classified as Clostridium have been reclassified in other genera.
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