Neuroscience

Brain research reveals a circuit for cocaine relapse

Approximately 1.5 million Americans use cocaine in a given year, according to the National Institute on Drug Abuse. Many are repeat users. Unfortunately, there are currently no FDA-approved medicinal treatments for cocaine ...

Psychology & Psychiatry

Menstrual cycle phase influences cocaine craving

Menstrual cycle may influence addiction risk in women, according to a new study in Biological Psychiatry by researchers at the National Institute on Drug Abuse and University of Maryland School of Medicine. In female rats, ...

Genetics

Gene therapy via skin protects mice from lethal cocaine doses

There are no approved medications to treat either cocaine addiction or overdose. Frequent users tend to become less and less sensitive to the drug, leading to stronger or more frequent doses. The typical result is addiction. ...

Addiction

Bile acids from the gut could help to treat cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb ...

Neuroscience

A gene required for addictive behavior

Cocaine can have a devastating effect on people. It directly stimulates the brain's reward center, and, more importantly, induces long-term changes to the reward circuitry that are responsible for addictive behaviors. Alban ...

Neuroscience

Study illuminates serotonin contributions to cocaine's allure

Once a hip drug of the '70s and '80s party scene, cocaine is not only making a comeback, it's proving its staying power thanks to its potent allure. In fact, Drug Enforcement Administration officials say that traffickers ...

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