Oncology & Cancer

Fatal brake failures: Tumorigenesis in the colon

Two genes normally work together to suppress the development of colon cancer. Their combined loss favors tumorigenesis and stimulates the formation of metastases.

Oncology & Cancer

Larotrectinib: Targeting DNA in cancer therapy

While other toddlers her age were fighting naptime, two-year-old Michelle was battling an aggressive, life-threatening cancer. Doctors at Children's Hospital Los Angeles saved her life in an epic battle, wielding what is ...

Oncology & Cancer

How obesity drives colon cancer in mice

Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, ...

Oncology & Cancer

Restricting a key cellular nutrient could slow tumor growth

Remove tumor cells from a living organism and place them in a dish, and they will multiply even faster than before. The mystery of why this is has long stumped cancer researchers, though many have simply focused on the mutations ...

Oncology & Cancer

Colon cancer cells use mysterious RNA strands to avoid cell death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. Unlike other RNAs, the intriguing strands ...

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