Oncology & Cancer

Drug combination gets advanced liver cancer patients to surgery

A combination of the kinase-inhibitor drug cabozantinib and the immunotherapy drug nivolumab can make curative surgery possible in some liver cancer patients who would normally not be considered surgery candidates.

Oncology & Cancer

Smart combination therapy for liver cancer tackles drug resistance

Liver cancer is one of the most common cancer types worldwide and is especially common in China. A collaborative effort between researchers at the Netherlands Cancer Institute and Shanghai using CRISPR/Cas has led to the ...

Oncology & Cancer

New immunotherapy drug effective for melanoma, other cancers

A new immune checkpoint inhibitor has proven effective in helping save the lives of advanced melanoma patients, a breakthrough that could extend to the treatment of other cancers. Relatlimab is the first immunotherapy treatment ...

Diseases, Conditions, Syndromes

Tailor-made therapy of multi-resistant tuberculosis

Globally, tuberculosis is the most common bacterial infectious disease leading to death. The pathogen causing tuberculosis, Mycobacterium tuberculosis, has a number of peculiarities. One is that it is growing very slowly. ...

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Combination therapy

In contemporary usage, the expression combination therapy most often refers to the simultaneous administration of two or more medications to treat a single disease, but the expression is also used when other types of therapy are used at the same time.

Conditions treated with combination therapy include tuberculosis, leprosy, cancer, malaria, and HIV/AIDS.

Combination therapy may seem costlier than monotherapy in the short term but causes significant savings: lower treatment failure rate, lower case-fatality ratios, slower development of resistance and consequently, less money needed for the development of new drugs.

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