As population exploded, more rare genes entered human genome

(Medical Xpress) -- As the Earth's human population has skyrocketed since the rise of agriculture some 10,000 years ago -- to 7 billion people from a few million -- so, too, has the number of rare genetic variants.

Inflammatory disorders

Drug resistance signature discovered in Crohn's disease

By mapping out more than 100,000 immune cells in patients with Crohn's disease, Mount Sinai researchers have discovered a signature of cells that are involved in a type of the disease that does not respond to treatment, according ...


Algorithm identifies networks of genetic changes across cancers

The algorithm, called Hotnet2, was used to analyze genetic data from 12 different types of cancer assembled as part of the pan-cancer project of The Cancer Genome Atlas (TCGA). The research looked at somatic mutations—those ...

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Computational biology

Computational biology is an interdisciplinary field that applies the techniques of computer science, applied mathematics and statistics to address biological problems. The main focus lies on developing mathematical modeling and computational simulation techniques. By these means it addresses scientific research topics with their theoretical and experimental questions without a laboratory. It encompasses the fields of:

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