Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks. ...
Dec 2, 2016
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Researchers have solved a decade-long mystery about a critical protein linked to Parkinson's disease that could help to fast-track treatments for the incurable disease.
Dec 23, 2021
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Scientists at The Scripps Research Institute have determined the structure of a critical protein from the Marburg virus, a close cousin of Ebola virus. These viruses cause similar diseases and are some of the deadliest pathogens ...
Sep 13, 2012
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American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design—blocking a molecular "scissor" that the virus uses for virus production and to disable ...
Oct 16, 2020
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Researchers identify an underlying molecular process that causes a genetic form of non-syndromic deafness in a new study that also suggests affected families may be at risk of damage to other organs.
Aug 27, 2013
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(Medical Xpress)—Despite urgent need and tremendous scientific effort, researchers have yet to discover a vaccine for HIV that adequately protects humans from infection. But some people don't need one. For reasons not completely ...
Nov 9, 2012
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(Medical Xpress)—Many diseases are multifactorial and can not be understood by simple molecular associations alone. Alzheimer's disease (AD)is associated with toxic transformations in two classes of protein,amyloid beta ...
Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...
Mar 31, 2013
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(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation factor 6 (ARF6) ...
Mar 5, 2013
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Clinical studies have demonstrated a strong association between Alzheimer's disease (AD) and delirium. A change to the Tau protein, which can lead to the formation of tangles in brain, is one of the hallmarks of AD pathology, ...
Jul 8, 2022
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