Immunology
Harnessing the power of a parasite that can stop pain
For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.
Nov 30, 2023
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News tagged with cutaneous leishmaniasis
Immunology
Uncovering the role of skin microbiome and immune response in cutaneous leishmaniasis
The parasitic disease leishmaniasis is found primarily in Central and South America, the Mediterranean region, the Middle East, and Central Asia and is transmitted to humans by a sand fly. An estimated 1.5 million new cases ...
Oct 24, 2023
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Diseases, Conditions, Syndromes
Texas sand fly may carry parasites that cause disfiguring skin disease, study says
A tropical disease once seen almost exclusively in returning travelers is now being detected in Texas and the South in people with no international travel history—caused by a parasite strain that's different from the imported ...
Oct 24, 2023
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Diseases, Conditions, Syndromes
New study provides 'genetic fingerprint' indicating disease spread by sand flies may be on the rise in US
Scientists have new evidence that a tropical disease once seen almost exclusively in returning travelers is now being detected in the United States in people with no international travel history—and caused by a Leishmania ...
Oct 19, 2023
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Diseases, Conditions, Syndromes
Digging deeper into how vaccines work against parasitic disease
Scientists have established the effectiveness of vaccines they developed to prevent the disfiguring skin disease leishmaniasis in animal studies, and Phase 1 human trial planning is in motion for the most promising candidate.
Aug 31, 2023
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Diseases, Conditions, Syndromes
Finding what drives the spread of a severe parasitic disease in Eastern Africa
A newly funded Tropical Medicine Research Center at The Ohio State University will study factors that drive transmission and spread of visceral leishmaniasis, a serious parasitic disease in Eastern Africa that is fatal without ...
Sep 7, 2022
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Diseases, Conditions, Syndromes
Flower nectar offers new weapon against Leishmaniasis
The nectar of common plants such as sunflower contain bioactive agents that can inhibit the growth of Leishmania and could be used to help fight the potentially fatal disease caused by the parasite, say researchers.
Jun 2, 2022
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Diseases, Conditions, Syndromes
Study reveals structure of protein and permits search for drugs against neglected diseases
Brazilian researchers have managed to decipher the structure of a protein found in parasites that cause neglected tropical diseases, paving the way to the development of novel medications. Thanks to the discovery it will ...
Jan 7, 2021
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Medical research
Predicting treatment outcome for leishmaniasis
For patients with cutaneous leishmaniasis, a skin infection transmitted by a sand fly that can in some cases lead to painful and disfiguring ulcers, treatment can be grueling. The first-line therapy offered to many requires ...
Nov 20, 2019
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Diseases, Conditions, Syndromes
Topical cream found as less-toxic therapy to treat cutaneous leishmaniasis
Paromomysin-based topical treatments were shown to be effective in curing cutaneous leishmaniasis (CL), according to a randomized, double blind study conducted in Panama and published with PLOS Neglected Tropical Diseases.
May 2, 2019
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