Genetics

Diabetes-causing gene can be regulated like a rheostat

Researchers at the Centre for Genomic Regulation (CRG) and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes. The findings, published in Nature Cell Biology, highlight ...

Oncology & Cancer

Hallmark cancer gene regulates RNA 'dark matter'

A key genetic mutation that occurs early on in cancer alters RNA "dark matter" and causes the release of previously unknown RNA biomarkers for cancer early detection, a new study by UC Santa Cruz researchers published in ...

Genetics

New technique searches 'dark genome' for disease mutations

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's ...

Genetics

New tool enables scientists to interpret 'dark matter' DNA

Scientists at the Gladstone Institutes have invented a new way to read and interpret the human genome. The computational method, called TargetFinder, can predict where non-coding DNA—the DNA that does not code for proteins—interacts ...

Genetics

Cause of genetic disorder found in 'dark matter' of DNA

For the first time, scientists have used new technology which analyses the whole genome to find the cause of a genetic disease in what was previously referred to as "junk DNA". Pancreatic agenesis results in babies being ...

Parkinson's & Movement disorders

New effort to identify Parkinson's biomarkers

Last month, the National Institutes of Health announced a new collaborative initiative that aims to accelerate the search for biomarkers—changes in the body that can be used to predict, diagnose or monitor a disease—in ...

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