A new machine-learning method accurately identifies regions of the human genome that have been duplicated or deleted—known as copy number variants—that are often associated with autism and other neurodevelopmental disorders. ...
Jul 10, 2019
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98
Glioblastoma (GBM) is the most common and aggressive form of brain cancer. Response to standard-of-care treatment is poor, with a two-year survival rate of only 15 percent. Research is beginning to provide a better understanding ...
Apr 23, 2018
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44
Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial ...
Jan 18, 2018
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481
A new University of Colorado Boulder study has shown that some dividing human cells are "kicking the can down the road," passing on low-level DNA damage to offspring, causing daughter cells to pause in a quiescent, or dormant, ...
May 17, 2017
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109
Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic disorders, including Down Syndrome. The condition is also the leading cause ...
Apr 6, 2017
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4
When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties. Such "asymmetric ...
Jul 1, 2016
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213
Several new malaria drugs under development share a common feature: they promote an influx of sodium ions into Plasmodium parasites that have invaded red blood cells and multiply there. A study published on May 26th in PLOS ...
May 26, 2016
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37
Follicular helper T cells (Tfh cells), a rare type of T cells, are indispensable for the maturation of antibody-producing B cells. They promote the proliferation of B cells that produce highly selective antibodies against ...
May 2, 2016
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41
The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children's Research Hospital have discovered that the production of daughter cells with different roles in the immune system ...
Apr 11, 2016
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143
Can any cancer cell form another tumor, or is it only select cancer stem cells that give rise to new cancer cells? The answer, a new study finds, is both.
Nov 30, 2015
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125
