Brain stimulation decreases involuntary shaking, researcher finds

Neurosurgical treatment with deep brain stimulation in a relatively new target area has been shown to relieve involuntary tremors in Parkinson's disease and Essential Tremor for up to at least five and 10 years after treatment ...

Parkinson's & Movement disorders

Parkinson's research: New hope when treatment options seem exhausted

As Parkinson's progresses, more invasive therapies are used, for example, those that require brain surgery. When these therapies no longer deliver the desired results, physicians often conclude that treatment options are ...


Neural circuit location of strong sense of discomfort found

Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure ...


Brain control in infancy linked to cognitive ability in toddlers

In a new study, Yale researchers offer a look into how infants' brains work and change over time, and how these processes can be disrupted by preterm birth. The findings, the researchers say, could point to treatments that ...

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Deep brain stimulation

In neurotechnology, deep brain stimulation (DBS) is a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain. DBS in select brain regions has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders such as chronic pain, Parkinson’s disease, tremor and dystonia. Despite the long history of DBS, its underlying principles and mechanisms are still not clear. DBS directly changes brain activity in a controlled manner, its effects are reversible (unlike those of lesioning techniques) and is one of only a few neurosurgical methods that allows blinded studies.

The Food and Drug Administration (FDA) approved DBS as a treatment for essential tremor in 1997, for Parkinson's disease in 2002, and dystonia in 2003. DBS is also routinely used to treat chronic pain and has been used to treat various affective disorders, including major depression. While DBS has proven helpful for some patients, there is potential for serious complications and side effects.

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