Parkinson's & Movement disorders

Parkinson's disease can affect the eyes, and here's what we know so far

Parkinson's disease is the second most common neurodegenerative disease, affecting over 10 million people worldwide. It's characterized by changes in movement, including tremors, and slower and more rigid movements. But researchers ...

Parkinson's & Movement disorders

Researchers stimulate improvements in Parkinson's treatment

New research led by QIMR Berghofer Medical Research Institute has identified ways to make the most widely-used advanced treatment for Parkinson's disease—deep brain stimulation therapy—more effective and safer.

Neuroscience

How experiencing traumatic stress leads to aggression

Traumatic stress can cause aggression by strengthening two brain pathways involved in emotion, according to research recently published in JNeurosci. Targeting those pathways via deep brain stimulation may stymie aggression ...

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Deep brain stimulation

In neurotechnology, deep brain stimulation (DBS) is a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain. DBS in select brain regions has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders such as chronic pain, Parkinson’s disease, tremor and dystonia. Despite the long history of DBS, its underlying principles and mechanisms are still not clear. DBS directly changes brain activity in a controlled manner, its effects are reversible (unlike those of lesioning techniques) and is one of only a few neurosurgical methods that allows blinded studies.

The Food and Drug Administration (FDA) approved DBS as a treatment for essential tremor in 1997, for Parkinson's disease in 2002, and dystonia in 2003. DBS is also routinely used to treat chronic pain and has been used to treat various affective disorders, including major depression. While DBS has proven helpful for some patients, there is potential for serious complications and side effects.

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