Diseases, Conditions, Syndromes

Dexamethasone trial results confirm COVID-19 benefits but also risks

The keenly-awaited full results from a UK trial of the steroid dexamethasone were published Friday, confirming its life-saving benefits for COVID-19 patients on ventilators but suggesting it may cause harm if given too early.

Diseases, Conditions, Syndromes

WHO urges dexamethasone boom for worst virus cases

The World Health Organization called on Monday for a rapid increase in production of dexamethasone, a cheap steroid which has been shown to reduce deaths in critically ill coronavirus patients.

Medical research

Cytokine implicated in HLH treatment resistance

Scientists at St. Jude Children's Research Hospital, UCSF Benioff Children's Hospitals and Baylor College of Medicine are investigating how to best treat hemophagocytic lymphohistiocytosis (HLH), a rare immune disorder. Their ...

Medications

Common steroid could soften up tumors for chemo

A common drug used to alleviate side effects of cancer treatment may also make the treatment more successful if given beforehand, report a consortium of research institutions including the University of Connecticut.

Medications

Daratumumab cuts risk for progression in multiple myeloma

(HealthDay)—For patients with newly diagnosed multiple myeloma, the addition of daratumumab to lenalidomide and dexamethasone is associated with a reduced risk for disease progression or death, according to a study published ...

Oncology & Cancer

Addition of elotuzumab ups PFS in refractory multiple myeloma

(HealthDay)—For patients with multiple myeloma in whom treatment with lenalidomide and a proteasome inhibitor has failed, progression-free survival (PFS) is longer in those receiving the immunostimulatory monoclonal antibody ...

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