Diseases, Conditions, Syndromes

New treatment target for diabetic kidney disease

(Medical Xpress) -- UC Davis investigators have shown that blocking a specific receptor pathway could slow or even prevent diabetic nephropathy — an often fatal complication of diabetes for which there are few good treatment ...

Diseases, Conditions, Syndromes

Drug effective in treating kidney disease in diabetic patients

Researchers at the University of California, San Diego School of Medicine, the National Institutes of Health (NIH) and the Mayo Clinic have published promising results of a clinical study using an experimental anti-fibrotic ...

Diseases, Conditions, Syndromes

Research aims to prevent diabetic kidney failure

The enzyme arginase-2 plays a major role in kidney failure, and blocking the action of this enzyme might lead to protection against renal disease in diabetes, according to researchers.

Diabetes

Low HDL cholesterol ups risk of diabetic nephropathy

(HealthDay) -- High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for the development of diabetic nephropathy, but not retinopathy, in patients with type 2 diabetes, according to research published ...

Medical research

Researchers replicate human kidney gene changes in mouse model

University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according ...

Medications

Promising kidney drug fails in large clinical trial

What was hoped to be a promising new drug to protect the kidneys has failed to benefit diabetes patients with kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology ...

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