Medications

Dimethyl fumarate linked to development of PML

(HealthDay)—An active ingredient in some psoriasis and multiple sclerosis medications, dimethyl fumarate, has been linked to two cases of progressive multifocal leukoencephalopathy (PML), according to two letters published ...

Medications

Multiple sclerosis therapy found to also improve gut flora

A medication used to treat multiple sclerosis (MS) also has a beneficial effect on the composition of the intestinal flora, according to researchers from the University of Basel and the University Hospital Basel. Conversely, ...

Medical research

A tool to interrogate a new class of drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation ...

Diseases, Conditions, Syndromes

Researchers investigate how the mpox virus infiltrates brain cells

A multidisciplinary team at the University of Alberta is seeking to understand how monkeypox (mpox) virus may be causing neurological symptoms in people affected by the global outbreak of mpox disease, declared by the World ...

Neuroscience

Rituximab tops other disease-modifying tx options in MS

(HealthDay)—Rituximab has better efficacy and lower discontinuation rates than other disease-modifying treatment (DMT) choices for newly diagnosed relapsing-remitting multiple sclerosis (RRMS), according to a study published ...

Medications

Dimethyl fumarate for MS: Added benefit is not proven

Dimethyl fumarate (trade name: Tecfidera) has been approved since January 2014 for adults with relapsing remitting multiple sclerosis (RRMS). In an early benefit assessment pursuant to the Act on the Reform of the Market ...

Neuroscience

Treatments compared for pediatric-onset multiple sclerosis

More patients with pediatric-onset multiple sclerosis (POMS) are free of new or newly enlarging (N or NE) T2 hyperintense lesions with dimethyl fumarate (DMF) versus interferon β-1a (IFNβ-1a) treatment, and the annualized ...

page 1 from 2