Medical research

Computer model could help test new sickle cell drugs

A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease. The model, described in a paper published in Science Advances, could ...

Immunology

Treating inflammation with inflammation

Scientists at the Keenan Research Centre for Biomedical Science (KRCBS) have uncovered a new potential approach to treat multiple types of autoimmune disease including arthritis in lab models.

Diseases, Conditions, Syndromes

3-D miniature livers lead the way to patient-specific drug discovery

The human liver is a vital organ involved in multiple functions. Because susceptibility to liver diseases is highly variable among patients, researchers from Tokyo Medical and Dental University (TMDU) and Cincinnati Children's ...

Parkinson's & Movement disorders

Can gut infection trigger Parkinson's disease?

A new study by Montreal scientists published today in Nature demonstrates that a gut infection can lead to a pathology resembling Parkinson's disease (PD) in a mouse model lacking a gene linked to the human disease.

Diseases, Conditions, Syndromes

Puzzling brain disease could now be better diagnosed, treated

Scientists have developed an animal model that may provide a path toward improving the diagnosis and treatment of the devastating brain disease chronicled in the bestselling autobiography "Brain on Fire." The book, along ...

Immunology

How to equip the brake of immunity

The immune system is indispensable for defense against invading pathogens, but its aberrant activation may lead to autoimmune diseases. Regulatory T cells play a crucial role in preventing excess immune activation; mice without ...

Health

Doctors need nutrition education, says commentary

Nutrition knowledge is essential for today's physicians, according to a JAMA Internal Medicine commentary published July 1. The commentary—authored by Neal Barnard, MD, president of the Physicians Committee for Responsible ...

Medications

New method divides patients with ulcerative colitis in groups

Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups. The findings ...

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