Alzheimer's disease & dementia

Alzheimer's drug candidates reverse broader aging, study shows

In mouse models of Alzheimer's disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, Salk researchers have shown how these compounds can also slow ...

Medications

Laboratory to join ATOM to transform drug discovery with AI

According to the National Cancer Institute, approximately 38 percent of men and women will be diagnosed with cancer at some point in their lives. The current process for drug discovery is slow and sequential, and often involves ...

Medical research

Reinvigorating the clinical drug pipeline for TB

A research team led by scientists from the Broad Institute has uncovered a novel group of chemical inhibitors that can kill the bacteria that causes tuberculosis (TB). Importantly, these chemical compounds take aim at a previously ...

Medical research

Scientists identify the causes of cortisone induced side effects

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich (LMU), partners in the German Center ...

Medical research

Scientists present an effective drug toxicity prediction method

Researchers from Skoltech (Maxim Fedorov's group, CDISE) and the German Research Center for Environmental Health, Helmholtz Zentrum München (HMGU; Igor Tetko's group) have developed an enhanced drug candidate toxicity prediction ...

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