With the United States facing a high number of drug shortages, a Chinese company may help to boost the supply of one in particular, the chemotherapy agent cisplatin.
Jun 5, 2023
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A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal ...
Mar 14, 2022
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The cancer drug cisplatin can save children's lives, but often with the side effect of hearing loss. Now a new study shows that young children are especially vulnerable, and the hearing damage may begin early in the course ...
Sep 28, 2021
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University of Alberta scientists have identified a receptor in cells that could be key to preventing permanent hearing loss in childhood cancer survivors who are being treated with the drug cisplatin. The researchers believe ...
May 14, 2021
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Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several ...
Mar 13, 2020
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Adding a drug that targets a molecular vulnerability in pancreatic cancer could provide substantial benefit to patients, according to a clinical trial study by the HonorHealth Research Institute and the Translational Genomics ...
Oct 3, 2019
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A team of pharmacists and chemists from the National University of Singapore (NUS) has developed a new anti-cancer drug that has less toxic effects to the kidneys. The new drug works like a "magic bullet" that is delivered ...
Sep 18, 2019
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Many chemotherapy drugs kill cancer cells by severely damaging their DNA. However, some tumors can withstand this damage by relying on a DNA repair pathway that not only allows them to survive, but also introduces mutations ...
Jun 6, 2019
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Yale School of Medicine researchers have found that the progression of acute kidney injury to chronic kidney disease (CKD) caused by use of the chemotherapy drug cisplatin is due to unresolved injury and sustained activation ...
Mar 27, 2019
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Despite being studied for decades, the chemotherapy drug cisplatin is revealing new aspects of how it works. Researchers at Winship Cancer Institute of Emory University have identified an enzyme responsible for making tumors ...
Jul 19, 2018
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