Medical research

Researchers discover new compound that promotes lung health

A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue. If the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may ...

Oncology & Cancer

Dozens of non-oncology drugs can kill cancer cells

Drugs for diabetes, inflammation, alcoholism—and even for treating arthritis in dogs—can also kill cancer cells in the lab, according to a study by scientists at the Broad Institute of MIT and Harvard and Dana-Farber ...

Neuroscience

Speeding up drug discovery for brain diseases

A research team led by Whitehead Institute scientists has identified 30 distinct chemical compounds—20 of which are drugs undergoing clinical trial or have already been approved by the FDA—that boost the protein production ...

Diabetes

New insight into the biology of insulin release

In a new study, Yale researchers challenge a long-held assumption about how insulin-producing cells in the pancreas sense and respond to glucose. Their findings could lead to changes in the way that scientists approach the ...

Medical research

Reinvigorating the clinical drug pipeline for TB

A research team led by scientists from the Broad Institute has uncovered a novel group of chemical inhibitors that can kill the bacteria that causes tuberculosis (TB). Importantly, these chemical compounds take aim at a previously ...

Oncology & Cancer

Balance of two enzymes linked to pancreatic cancer survival

Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...

Diseases, Conditions, Syndromes

Team makes Zika drug breakthrough

A team of researchers from Florida State University, Johns Hopkins University and the National Institutes of Health has found existing drug compounds that can both stop Zika from replicating in the body and from damaging ...

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