A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University of China has developed a remarkable double-layer polysaccharide hydrogel (DPH) that promises to revolutionize the field of intestine-targeted ...
Sep 28, 2023
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The Ultrasound and Elasticity Imaging Laboratory, led by Elisa Konofagou, Robert and Margaret Hariri Professor of Biomedical Engineering, develops novel, ultrasound-based techniques for both imaging and therapeutic applications.
Sep 13, 2023
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Researchers have found a way to use a simple, non-invasive scan to tell whether an experimental approach to enhance treatment for breast cancer is effective. The new research, led by scientists at The Institute of Cancer ...
Sep 6, 2023
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Researchers at University of Galway and Massachusetts Institute of Technology (MIT) have pioneered a new, intelligent medical device which senses its environment and can adapt to release drugs as required, despite surrounding ...
Aug 30, 2023
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According to data from Statistics Korea, cancer accounted for the majority of deaths in Korea in 2021, constituting 26% of all recorded cases. Similarly, cancer was the primary cause of death in 2020. Among the various types ...
Aug 14, 2023
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Researchers have proposed using emulsion microgels for drug delivery to the bladder. This promises to make the treatment of urinary tract infections more effective and less painful. The microgels contain whey protein capable ...
Jul 27, 2023
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What makes the vital layer of protective cells around the brain and spinal cord—the blood-brain barrier—more or less permeable has been one of the more mystifying questions in neuroscience.
Jul 13, 2023
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Acoustic tweezers can control target movement through the interaction of momentum between an acoustic wave and an object. Due to their high tissue penetrability and strong acoustic radiation force, such tweezers overcome ...
Jul 5, 2023
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A team of medical scientists and engineers affiliated with several institutions in China has developed a microneedle-based patch that adheres to surfaces to inject drugs, inspired by the mechanism used by the blue-ringed ...
Probiotics can help maintain a healthy gut microbiome or restore populations of "good bacteria" after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy for certain intestinal ...
Jun 21, 2023
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Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absorption, distribution and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance. Most common methods of delivery include the preferred non-invasive peroral (through the mouth), topical (skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal) and inhalation routes. Many medications such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptible to enzymatic degradation or can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be therapeutically effective. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunizations are based on the delivery of protein drugs and are often done by injection.
Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation. Types of sustained release formulations include liposomes, drug loaded biodegradable microspheres and drug polymer conjugates.
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