Medical research

Timed release of turmeric stops cancer cell growth

A Washington State University research team has developed a drug delivery system using curcumin, the main ingredient in the spice turmeric, that successfully inhibits bone cancer cells while promoting growth of healthy bone ...

Medical research

Opioid alternative? Taming tetrodotoxin for precise painkilling

Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and overdose. While conventional local anesthetics block pain very effectively, they wear off quickly ...

Oncology & Cancer

New drug delivery system suppresses tumors in mice

As cancer treatment gets more sophisticated, we need more refined drug delivery systems that can simultaneously deliver multiple drugs with different chemical makeups.

Medical research

Inhaled nanoparticles could treat lung cancer

QUT pharmaceutical scientist Dr. Nazrul Islam, from School of Clinical Sciences, said lung cancer was one of the most common cancers globally and one of the deadliest, being a leading cause of cancer deaths.

Oncology & Cancer

Scientists compare methods of drug delivery to malignant tumors

A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University (Nizhny Novgorod) has analyzed available methods of targeted drug delivery to malignant tumors. Individual approaches to ...

Ophthalmology

Contact lens-based antihistamine delivery effective

(HealthDay)—A contact lens (CL)-based drug delivery system is effective for therapeutic delivery of the antihistamine ketotifen, according to a study published online March 19 in Cornea.

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Drug delivery

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absorption, distribution and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance. Most common methods of delivery include the preferred non-invasive peroral (through the mouth), topical (skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal) and inhalation routes. Many medications such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptible to enzymatic degradation or can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be therapeutically effective. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunizations are based on the delivery of protein drugs and are often done by injection.

Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation. Types of sustained release formulations include liposomes, drug loaded biodegradable microspheres and drug polymer conjugates.

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