Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have developed a small-molecule drug that prevents weight gain and adverse liver changes in mice fed a high-sugar, high-fat ...
Mar 21, 2023
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254
Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in ...
Mar 14, 2023
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34
Scientists at the National Institutes of Health and Massachusetts General Hospital in Boston have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs. ...
Mar 13, 2023
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39
The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections. Researchers have now discovered that a new class of oral ...
Mar 9, 2023
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93
While substance use disorder (SUD) remains a clinically and socially devastating condition in the U.S. and worldwide, the phenomenon of how individuals transition from recreational to compulsive drug use is yet to be fully ...
Mar 8, 2023
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86
For people with alcohol use disorder (AUD), there is a constant, vicious cycle between changes to the brain and changes to behavior. AUD can alter signaling pathways in the brain; in turn, those changes can exacerbate drinking.
Mar 6, 2023
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Scientists have revealed details of the discovery of new inhibitors of the BCL6 protein, which is involved in driving several cancer types including the blood cancer B-cell lymphoma.
Feb 9, 2023
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41
Microglia are cells that are central to both brain health as well as disease progression in many neurological conditions. Normally, microglia stabilize the brain by clearing out damaged neurons and protein plaques often associated ...
Jan 25, 2023
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67
A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein that prevents bone growth. ...
Dec 19, 2022
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69
For some of the powerful drugs used to fight infection and cancer, there's only a small difference between a healing dose and a dose that's large enough to cause dangerous side effects. But predicting that margin is a persistent ...
Dec 7, 2022
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