Elevated blood pressure can cause a condition known as perivascular fibrosis, where the outside wall of a blood vessel thickens due to connective tissue build-up. Although recent data has suggested that the thickening is ...
Apr 21, 2022
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Most autoimmune diseases are easy to diagnose but hard to treat. A paper published today in Science proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune disease.
Apr 7, 2022
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An important aspect of drug discovery involves determining how well a drug binds to its target (protein) molecule. Typically, this step involves aligning a 3D structure of a drug and its target protein at various configurations ...
Apr 5, 2022
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While vaccination and public education concerning the transmission of the coronavirus causing COVID-19 have been at the forefront of our response to the pandemic, there remains an urgent need for pharmaceutical interventions ...
Mar 24, 2022
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A multidisciplinary team of researchers from Roswell Park Comprehensive Cancer Center and Kaiser Permanente Northern California have identified the first pharmacogenomic marker for anthracyclines and HER2-targeting drugs, ...
Mar 23, 2022
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Scientists from St. Jude Children's Research Hospital have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors. Their research looked at the difference between their ...
Mar 22, 2022
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It takes 10 to 15 years and around US$1 billion to develop one successful drug. Despite these significant investments in time and money, 90% of drug candidates in clinical trials fail. Whether because they don't adequately ...
Feb 24, 2022
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Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors. In part because of its rapid and invasive ...
Feb 7, 2022
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Inhibition of Ubiquitin Specific Peptidase 47 (USP47) was identified as a novel therapeutic target for hematologic malignancies bearing mutant oncoprotein EZH2, according to scientists from the Hefei Institutes of Physical ...
Jan 27, 2022
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Hemp compounds identified by Oregon State University research via a chemical screening technique invented at OSU show the ability to prevent the virus that causes COVID-19 from entering human cells.
Jan 11, 2022
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