Medical research

Researchers solve structure of immune-evading HIV protein complex

The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor (Vif). OIST researchers Prof. Matthias Wolf and Dr. Takahide Kouno together with an international team of colleagues have now determined the ...

Neuroscience

New images capture unseen details of the synapse

Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer-scale models will help scientists ...

Neuroscience

How a highly unstable protein may lead to neurodegeneration

EPFL scientists have reproduced key features of pathological protein aggregates found in the brain of patients with Lou Gehrig's disease and other neurological diseases, providing insight into the underlying mechanism and ...

Diseases, Conditions, Syndromes

What you need to know about Nipah virus

A mysterious illness causing fevers and headaches and leading to rapid development of acute encephalitis (within a couple of weeks of symptom onset), caused an outbreak of nearly 300 reported cases and over 100 fatalities ...

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Electron microscope

An electron microscope is a type of microscope that uses a particle beam of electrons to illuminate a specimen and create a highly-magnified image. Electron microscopes have much greater resolving power than light microscopes that use electromagnetic radiation and can obtain much higher magnifications of up to 2 million times, while the best light microscopes are limited to magnifications of 2000 times. Both electron and light microscopes have resolution limitations, imposed by the wavelength of the radiation they use. The greater resolution and magnification of the electron microscope is because the wavelength of an electron; its de Broglie wavelength is much smaller than that of a photon of visible light.

The electron microscope uses electrostatic and electromagnetic lenses in forming the image by controlling the electron beam to focus it at a specific plane relative to the specimen. This manner is similar to how a light microscope uses glass lenses to focus light on or through a specimen to form an image.

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