Medical research

Finding the origin of congenital coronary fistulae

Scientists of the Department of Animal Biology of the University of Malaga have discovered the cellular mechanism that originates coronary arterio-ventricular fistulae, a congenital anomaly that, in severe cases, may result ...

Oncology & Cancer

How tumors transform blood vessels

Increasingly dense cell clusters in growing tumors convert blood vessels into fiber-filled channels. This makes immune cells less effective, as findings by researchers from ETH Zurich and the University of Strasbourg suggest. ...

Oncology & Cancer

Examining the cause of leukemia in trisomy 21

Leukemia (blood cancer) is a group of malignant and aggressive diseases of the blood-forming cells in the bone marrow. Very intensive chemotherapy and in some cases a bone marrow transplant are the only cure. Like all cancers, ...

Neuroscience

How to generate new neurons in the brain

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...

Diseases, Conditions, Syndromes

3D organoid models show brain mechanisms of Tourette syndrome

Tourette syndrome (TS) is a common disorder characterized by uncontrollable motor or vocal tics that manifests in childhood and can interfere with school performance, relationships, and quality of life. Using stem cells from ...

Arthritis & Rheumatism

How to rewind the clock on arthritic cartilage

A new study in Aging Cell describes how a key protein called Signal Transducer and Activator of Transcription 3 (STAT3) might turn back the clock on aging cartilage that leads to osteoarthritis.

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