Bacterial infections can lead to the formation of abscesses—pockets of dead cells and debris surrounded by inflammatory immune cells. Bacteria multiply within abscesses, causing more inflammation and further damage to surrounding ...
Jan 17, 2024
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Billions of years ago, as primitive lifeforms were becoming more complex, a selfish genetic component became a sort of genome colonizer. Using a copy-and-paste mechanism, this pernicious bit of code replicated and inserted ...
Dec 26, 2023
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187
A significant portion of mammalian genomes are composed of retrotransposable elements (REs). Unlike the previous hypothesis that these are "junk DNA," recent studies have shown that REs such as endogenous retroviruses (ERVs) ...
Sep 6, 2023
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Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers at DZNE have come to this conclusion based on studies of cell cultures. In ...
Aug 21, 2023
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The innate immune system fights infectious agents, and the alarm messenger interferon plays a central role in this. However, if interferon is produced in the absence of an infection, it can lead to autoimmune diseases. Researchers ...
Nov 8, 2022
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Researchers at Karolinska Institutet in Sweden have published new findings in the journal Cancer Discovery showing how pharmacological activation of the protein p53 boosts the immune response against tumours. The results ...
Jul 6, 2021
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National Institutes of Health scientists and their collaborators have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as ...
Jun 23, 2021
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The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota. This layer of cells plays a crucial role in water, electrolyte and nutrient absorption, while ...
Jun 8, 2020
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DNA "echoes" of viruses that infected our ancestors millions of years ago could help the immune system to identify and kill cancer cells, according to new research from Crick scientists.
Sep 20, 2019
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About eight percent of our DNA is viral in origin: remnants of ancient battles between infectious viruses and our ancestors. These so-called endogenous viruses are often perceived as a mere oddity with no clear biological ...
Mar 3, 2016
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