A compound, developed by a team including scientists from The University of Texas Health Science Center at San Antonio, kills a range of hard-to-treat cancer types in petri dishes and animal models by targeting a previously ...
Jun 2, 2022
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1092
It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins ...
May 6, 2022
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123
A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's disease and related ...
Mar 23, 2022
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498
Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School ...
Mar 15, 2022
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126
Multiple myeloma is a cancer of the bone marrow, with a life expectancy of less than 5 years post-diagnosis. Proteasome inhibitors, the therapeutic backbone of current treatments, are very effective in treating newly diagnosed ...
Jan 12, 2022
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18
UAB and Vall d'Hebron researchers identified the mechanism by which inhibitors of the ERK5 protein kinase impair the proliferation of cancer cells and induce their death. The results, obtained using human cancer cell lines, ...
Dec 21, 2021
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29
Exploring the mechanisms involved in sleep-dependent memory storage, a team of University of Michigan (U-M) cellular biologists found that RNAs associated with an understudied cell compartment in hippocampal neurons vary ...
Nov 25, 2021
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197
Mayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new Nature Immunology publication.
Nov 22, 2021
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85
Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...
Jul 20, 2021
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57
A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop metabolic disease during their lifetime, as suggested by previous ...
Jan 26, 2021
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