Immunology

Important regulator of immune system decoded

Our environment teems with microorganisms and viruses that are potentially harmful. The reason why we survive their daily attacks is the ability of the immune system to neutralize these invaders in numerous ways. Plasma cells ...

Genetics

Cellular stress process identified in cardiovascular disease

Combining the investigative tools of genetics, transcriptomics, epigenetics and metabolomics, a Duke Medicine research team has identified a new molecular pathway involved in heart attacks and death from heart disease.

Diabetes

Discovery may revolutionise diabetes treatment

Research published in the journal Nature Medicine on Monday by my team provides hope for a new approach to treating type 2 diabetes. In animal models of the disease, our treatment restores natural control of blood sugar.

Medical research

A new player in lipid metabolism discovered

(Medical Xpress)—Specially engineered mice that lacked a particular gene did not gain weight when fed a typical high-fat, obesity-inducing Western diet. Yet, these mice ate the same amount as their normal counterparts that ...

Medical research

Nicotine exploits COPI to foster addiction

A study in The Journal of General Physiology helps explain how nicotine exploits the body's cellular machinery to promote addiction. The findings could lead to new therapies to help people quit smoking.

Alzheimer's disease & dementia

New light shed on early stage Alzheimer's disease

The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important ...

Oncology & Cancer

Cancer cells co-opt immune response to escape destruction

Researchers at the University of California, San Diego School of Medicine report that tumor cells use stress signals to subvert responding immune cells, exploiting them to actually boost conditions beneficial to cancer growth.

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