Alzheimer's disease & dementia

pH imbalance in brain cells may contribute to Alzheimer's disease

Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer's disease may be a simple imbalance in acid-alkaline—or pH—chemistry inside ...

Neuroscience

Autism gene stunts neurons, but growth can be restored, in mice

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches ...

Neuroscience

Scientists eliminate key Alzheimer's feature in animal model

A study by UT Southwestern researchers finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer's disease. The finding, published in eLife, ...

Medical research

Researchers modify drug to enter cells and treat pain

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's ...

Genetics

Misregulated genes may have big autism role

A new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate in general autism ...

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