Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting ...
Aug 9, 2023
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Researchers have identified novel gelatinase substrates involved in astroglial barrier function. In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this ability is the gelatinases ...
Aug 9, 2023
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Researchers at the Francis Crick Institute have shown in lab-based experiments that variants of SARS-CoV-2, the virus that causes COVID-19, can affect the blood-brain barrier and damage brain cells in different ways. This ...
Aug 7, 2023
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A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, ...
Aug 3, 2023
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Anaplastic large cell lymphoma, a form of non-Hodgkin lymphoma, is the most common aggressive lymphoma in children. Chemotherapy and radiation fail to cure about 30% of cases. When tumors are driven by the oncogene ALK—which ...
Aug 3, 2023
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Blood vessels keep us alive. They are the highways that transport oxygen-rich blood and nutrients to all corners of our body—feeding our tissue and organs—while simultaneously removing toxic waste products.
Aug 1, 2023
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Scientists at UT Southwestern Medical Center and Children's Medical Center Dallas have discovered in mice how high cholesterol causes blood vessels to become inflamed, a necessary prerequisite for atherosclerosis—the "hardening ...
Jul 25, 2023
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What makes the vital layer of protective cells around the brain and spinal cord—the blood-brain barrier—more or less permeable has been one of the more mystifying questions in neuroscience.
Jul 13, 2023
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Therapeutic antibodies that cause aggressive tumors to become susceptible to treatment are being studied with the hope of one day changing the fate of patients who either relapse soon after cancer therapy or whose stubborn ...
Northwestern Medicine investigators have discovered a novel mechanism that regulates neutrophil recruitment into tissue during inflammation, which could be targeted to treat different inflammatory diseases and conditions, ...
Jun 30, 2023
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