Research led by Rockefeller University in New York investigated alternate targets for monoclonal antibodies to combat SARS-CoV-2 infections.
A new review suggests that higher-than-normal levels of an enzyme involved in blood clot prevention may be a common risk factor for developing COVID-19—a respiratory disease caused by the novel coronavirus SARS-CoV-2—in ...
Apr 16, 2020
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Roflumilast, a drug recently approved in the United States to treat severe chronic obstructive pulmonary disease (COPD), increases the production of a protein that causes inflammation, which possibly results in patients developing ...
Mar 23, 2015
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More than 20 million Americans undergo colonoscopy screenings every year, and in many of those cases, doctors end up removing polyps that are 2 cm or larger and require additional care. This procedure has greatly reduced ...
Mar 12, 2024
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Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum. The resulting cerebellar dysfunction leads patients to experience ...
Oct 3, 2022
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In a study published in the October 2022 issue of Brain, researchers from Rady Children's Institute for Genomic Medicine (RCIGM) and the University of California San Diego School of Medicine describe their discovery of a ...
Oct 27, 2022
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A huge colony of receptors must be optimally positioned and functioning on our muscle cells for our brains to talk with our bodies so we can walk and breathe.
Nov 28, 2016
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Immunologists have long been baffled by LPS, the bacterial lipopolysaccharide that helps form the cell walls of Gram-negative bacteria.
Jan 5, 2022
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Cancer treatments are suspected to accelerate certain aging processes in the body. A new study has found that indicators of such biological aging correlate with declines in cognitive function in women who had undergone breast ...
Nov 26, 2018
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A Ben-Gurion University of the Negev research group led by Prof. Ohad Birk has identified a gene whose defect specifically causes myopia or nearsightedness.
Sep 1, 2011
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Enzyme catalysis is the catalysis of chemical reactions by specialized proteins known as enzymes. Catalysis of biochemical reactions in the cell is vital due to the very low reaction rates of the uncatalysed reactions.
The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis. By providing an alternative reaction route and by stabilizing intermediates the enzyme reduces the energy required to reach the highest energy transition state of the reaction. The reduction of activation energy (ΔG) increases the number of reactant molecules with enough energy to reach the activation energy and form the product.
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