Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...
May 08, 2019
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New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight ...
Nov 14, 2018
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One of the many challenges in treating HIV is that the virus can lie dormant in cells, quietly evading immune detection until it suddenly roars to life without warning and begins replicating furiously. Salk Institute researchers ...
May 31, 2018
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Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry. The enzyme appears to drive ...
Jan 26, 2018
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A new approach to targeting key cancer-linked proteins, thought to be 'undruggable," has been discovered through an alliance between industry and academia.
Oct 19, 2017
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Northwestern Medicine scientists have discovered that the catalytic activity of the fly enzyme Trr and mammalian MLL3/MLL4—members of the COMPASS family of proteins central to gene expression—is not required for proper ...
Oct 02, 2017
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A naturally occurring human enzyme -called cyclophilin 40 or CyP40- can unravel protein aggregates that contribute to both Alzheimer's disease and Parkinson's disease, according to a study publishing June 27 in the open access ...
Jun 27, 2017
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Professor Seyun Kim's team from KAIST reported the mechanism by which cellular signaling transduction network is exquisitely controlled in mediating innate immune response such as sepsis by the enzyme IPMK (Inositol polyphosphate ...
May 04, 2017
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Researchers at University of California San Diego School of Medicine have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated ...
Oct 12, 2016
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Cancer is a group of more than 100 different diseases. All are driven by cells and genes that escape the normal process of division and begin their own plan to replicate in the body. Advances in genetics and molecular biology ...
Jul 08, 2016
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